This version uses updated MoM adjustment factors for first trimester PAPP-A and free ß hCG measurements in dichorionic and monochorionic twin pregnancies (Reference 1)
This version uses updated statistical parameters for nuchal translucency, first trimester PAPP-A and free ß hCG when calculating Down’s syndrome, trisomy 18 and trisomy 13 risks in dichorionic and monochorionic twin pregnancies (Reference 1)
This version uses updated MoM adjustment factors for first trimester PlGF measurements in dichorionic twin, monochorionic twin and IVF pregnancies (Reference 2)
A “Notification Options” feature is included. This feature provides a list of unreported patients who have a specified set of marker measurements or who remain unreported a specified number of days after the patient details were first entered
The Risk Analysis, Positive Rate, CUSUM and Re-tabulations charts can now be printed.
The Events Log and Missing Information table can now be exported to a file.

The principal change is a feature which shows the effect on a tabulation of the medians being updated.
Additional changes are improvements to the individual XPS/PDF file export.

The principal change is a feature which shows the effect on a tabulation of the medians being updated.

The free ß hCG and PAPP-A trisomy 18 lower truncation limits have both been reduced to 0.05 MoM.
Entries for previous trisomy 18 and previous trisomy 13 can be included in the Alpha data entry screen.
This version has additional features for user security including password expiry, lockout after a specified number of login failures and enforcing password complexity.

Wipe locks has been included as a security permission
Changes to the Persian calendar so that fewer key strokes are required:
Focus moves automatically from day to month and month to year after two characters have been entered (previously had to tab between fields)
Set button is activated by return key (do not need to move to set button and click on it)
Focus moves to next item after set button pressed (previously focus stayed in date field)
Ctrl + tab or Ctrl + enter open Persian calendar when focus in date field (don’t have to press “bird” symbol)
The option to report either the risk of early pre-eclampsia (pre-eclampsia occurring before 34 weeks) or the risk of all pre-eclampsia.
The option to derive gestational age measurements from crown rump lengths using the equation given by Sahota et al.
The option to use a log cubic regression equation for inhibin-A with four variable coefficients.
The regression facility includes the option to show confidence intervals around each observed median marker measurement and provides a measure of the goodness of fit of the regression equation to the observed measurements.

Plots of NT against CRL for a group of sonographers or addresses can be displayed either as individual charts or with all results plotted on one chart.
The median MoM and confidence intervals for a group of sonographers can be displayed on a chart.
The results from sonographer codes can be shown which were used in reports which included one or more selected addresses.
A warning is displayed if the number of NT scans performed is less than a minimum.
Groups of sonographers can be specified and saved.
The list of sonographer and address codes can be searched.
A tabulation or median analysis for the selected sonographer or address codes can be made directly from NT monitor.
Improvements have been made to the Patients screen:
Analyze-it queries can be specified in the advanced search.
Batches can be ordered alphabetically or chronologically.
Separate buttons for test and final reporting are provided.

In contingent test Low Risk, High Risk and Intermediate Risk appear in the result section of the report.

In contingent test Low Risk,High Risk and Intermediate Risk appear in the results section of the report.

The principal changes in this version are a feature which allows certain data entry fields to be mandatory before a report is made and improvements to the report designer with the ability of creating a pdf output.

The principal change in this version is that reports can be printed to PDF files.

An option is provided to use the Hadlock relationship for converting between crown rump length (CRL) and gestational age (GA)
An option is provided to show summary information about each batch on the Patients screen
Alpha can take into account the family history of pre-eclampsia and parity in the calculation of the pre-eclampsia risk estimate.
Performance estimates for pre-eclampsia screening can include previous history of pre-eclampsia, family history of pre-eclampsia and parity.
Performance estimates for Down’s syndrome screening can include nasal bone absence or presence.
Alpha 8 version of Outcome
The option to use an exponential regression equation using three variable coefficients for second trimester total hCG and free ß hCG.

The principal changes in this version are:
Alpha can take into account the family history of pre-eclampsia and parity in the calculation of the pre-eclampsia risk estimate.
Performance estimates for pre-eclampsia screening can include previous history of pre-eclampsia, family history of pre-eclampsia and parity.
Performance estimates for Down’s syndrome screening can include nasal bone absence or presence.
Alpha 8 version of Outcome
The option to use an exponential regression equation using three variable coefficients for second trimester total hCG and free ß hCG.

Alpha includes an adjustment factor for PAPP-A measurements in women with Insulin-dependent diabetes mellitus